Tag Archives: israel

23andme and the power of information

For a few months now I have been using a genetic testing service called 23andme (Wikipedia).  Their promise is quite simple:

Gain insight into your traits, from baldness to muscle performance. Discover risk factors for 97 diseases. Know your predicted response to drugs, from blood thinners to coffee.  And uncover your ancestral origins.

The process is very straightforward.  After sign up and paying a fee (+ shipping and handling) you get a small plastic tube.  Spit on it, send it via DHL back to their labs in the US and wait to get your results.

You do have to agree to a pretty hefty disclaimer, and there’s a reason for it.  23andme only provide genetic testing and related services and are not a medical services provider.  Furthermore, the information you can gather from this procedure can have profound consequences for you and your family: maybe there’s an inheritable disease doing the rounds in your folks (Alzheimer or Parkison have been thoroughly researched, e.g.), or you discover relatives you didn’t know you have (or indeed, find out you’re not related to who you thought you were).

Once you register you are granted access to their website to familiarize yourself with their interface and the possible results you could get.  Their service is divided into four parts: My Health (genetic disease carriers and drug response), My Ancestry (analysis of X-chromosome and mitochondrial DNA for genetic genealogy), Sharing and Community (“social genetics” features), and 23 and We (voluntary participation in genetic research through surveys).

The most interesting sections for me were the first two.  Regarding health I was able to confirm what I already knew from my family history plus a couple of things that I suspected but I had no certainty about such as the fact that I metabolize caffeine relatively slowly, which explains why I don’t need many cups of coffee to get my “latte high”.

The ancestry bit was also very interesting.  I know a fair amount regarding my ancestry up to my great-grandparents and there are a couple of things I can gather given the areas of Mexico where they come from, but unfortunately doing a full genealogical research European style is out of the question since records in Mexico have been destroyed or lost in the Independence War, the Mexican Revolution and the Cristero War.  What I found was that my mitochondrial DNA (basically my mom’s mom’s almost ad infinitum line) is Mexican Indian from the Pacific Ocean from the Ice Age migrations through the Bering Strait when the Americas was being first populated (phenotype doesn’t equal genotype, my mom looks more Caucasian than I do), while my X chromosome shows Middle Eastern (possibly Jewish or Lebanese) ancestry, which is also consistent with the recently documented migration of Spanish Jews to Northern Mexico to avoid the Spanish Inquisition.  Furthermore, while the majority of my genetic markers are European, I do have a third of Asian/Native American (back to the Bering Strait bit) ancestry plus a smattering of African inheritance.  It all makes relative sense based of what I know of my family’s history.

Basically what I learned in my lessons of Mexican History through high school is not only correct, it shows in me.

Unfortunately 23andme’s reference database is not perfect, but thankfully the Mexican Genomics Institute is doing a very good job in analyzing what people from the Bravo to the Usumacinta Rivers carry in their genes.  All hail Saint Google :).

Through their community features the service calculates other possible genealogical matches (basically people who could be related to you who have also used the service). I’ve found mostly Mexican-Americans (obvious as their service is based in the US and they do not ship to Mexico due to our awesome customs officials) plus a smattering of people with Spanish ancestry and a lone Colombian with (I suppose) Amerindian ancestry.

Then there’s the research bit.  It’s basically a bunch of surveys they use to help in correlating the presence of certain genetic markers with physical or medical traits.  It’s interesting but I haven’t used the service long enough to have my answers help in any medical discoveries.

The only blemish to the whole thing is that we could get test results for my son.  He’s so young that his drool is too diluted (after all the little man is teething), which means they cannot extract enough genetic material for analysis. With the way things are developing, I wouldn’t be surprised if they’re able to do it in a year or two.

All in all, a very interesting experience even if I’m just really getting started.  If you want to know more about factors that could affect your health plus your ancestry and are not afraid of the power of information I truly recommend it. Other services only do one or the other.

The reactions to swine flu in Mexico (part II)

Roman Catholic masses were cancelled throughout the city, museums were closed and football matches were played behind close doors (my team, Chivas, tied) to avoid the creation of crowds.  People have been generally very calm from what I understand, stayed home and there is no panic shopping, but the streets are rather empty for a city of over 20 million people (some pictures here).  If you understand Spanish, a great chronicle of the past two days can be found here and here.  The city is not afraid, and people still make fun of the situation from time to time.

Video rentals and video stores were doing brisk business yesterday, and schools are closed until May 6th (May 1st and 5th are holidays anyway).  Military personnel have been handling masks around the city and now everybody is bracing themselves for tomorrow: will people go to work or will they home office (those who can)?

The Finnish media have complained about the slow Mexican response to the outbreak, but they seem to ignore that even the National University (UNAM) doesn’t have the equipment needed to distinguish this new virus from its old, previously known cousins and with the normal flu season just ending, there was no cause for concern.  On the other hand the World Health Organisation has praised the Mexican response.

There are confirmed cases in Mexico, the US, Canada and New Zealand, and suspected cases in France, Spain, UK & Israel (map here).  Deaths have only happened in Mexico, and even there two thirds of the 1200 cases have already been released from hospital.  According to some information in the Mexican media, vaccines don’t work, but antivirals such as Tamiflu do.  Airports haven’t been closed, but there is more stringent screening in Singapore, Hong Kong and Japan from passengers coming over from North America.

There are two different hypothesis of the origin of the virus: one points to it having started in a farm in Texas and then crossed over to the border, the other one points to farms in Perote, Veracruz, Mexico.  None has been confirmed.

If you want to know more in real time, you can follow @Veratect and @zolliker (in Spanish) on Twitter.

Against the World Music category

Anybody who knows me a little bit (or has seen my profile at Last.fm) has probably realised that my musical taste is quite varied.  On any given day I could be listening to raï, ranchera, punk, samba, rock, jazz, metal, classical music, ska, axé, or electronica from Mexico, Japan, Brazil, Algeria, France, Belgium, Israel, India, Canada, Argentina, Egypt, China, etc… which if they’re not your usual Anglo-Saxon pop-rock will usually be clumped together into World Music, with very awkward results.

For example, with the current version of iTunes you have a “Genius” feature that promises to make perfect playlists for you.  However, the database they use seems to have been made by the record companies instead of users, so when it does find the music I have (which is less often than I would expect), if I ask to create a Genius playlist out of e.g. one of my favourite Mexican rock bands it will put it together with Mexican & Argentine traditional music too since they’re “Latin”, something akin to lumping James Brown together with Enya because they come from the English-speaking world.  It gets even better when I try it with some of my favourite samba artists, as they will be lumped together  with salsa, raï, Bollywood and tango acts because they are “World Music”, even if I do have plenty of MPB (Música Popular Brasileira) to make a list with.

David Byrne said it best: he hates world music.

Palestinian scarf


selfportrait, originally uploaded by hme.

I will admit one thing: I have been to both Israel and an Arab country and liked both, including the people of both places. I will take no sides.

I bought a scarf similar to this in London. The following quote from Wikipedia: “As with other articles of clothing worn in wartime, such as the T-shirt and khaki pants, the keffiyeh has recently become both ethnic and military chic among non-Arab hipsters in the West, who may be uninterested in either politics or the military. In Europe and major cities of the Americas and Australia, the black-and-white keffiyeh has become a youth fashion accessory, often worn as a scarf.”

This is the sense in which I wear it, I’m neither pro-Israel or pro-Palestine, I’m pro-peace.

However, since I’m not exactly Caucasian, wearing it in Helsinki or Brussels people think that I’m Arab, instead of just following a fashion that other people follow as well. I find it rather stupid, and very annoying.